Transperineal Biopsy
A transperineal biopsy is a biopsy procedure in which a small tissue sample is taken from the prostate for examination under a microscope. The sample is collected using a thin needle inserted through the skin of the perineum (between the scrotum and anus) and into the prostate. Imaging is obtained by an ultrasound probe passed into the rectum. Imaging is provided by an ultrasound probe placed in the rectum. This approach can improve sampling, particularly in men who had a previous negative (TRUS) biopsy.
One of the key advantages of the transperineal method is the lower risk of infection. The skin of the perineum can be easily disinfected by routine surgical preparation, whereas TRUS biopsies carry a higher risk of infection because the needle passes through the rectal wall. In addition, the transperineal path allows to ventral prostate areas that are often missed with the standard transrectal approach.
BiopSee® Solution: U/S-MRI Fusion & Navigated TP Biopsy
By combining ultrasound with MRI through fusion, Biopsee® enables precise navigation during transperineal biopsy. This targeted approach improves accuracy and supports reliable cancer detection.
Clinical Results
General detection rate: 58%-70%
Targeted mpMRI-suspicious lesions detection rate: 86%-100%4
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4 Hadaschik BA, Kuru TH, Tulea C, Rieker P, Popeneciu IV, Simpfendörfer T, et al. A Novel Stereotactic Prostate Biopsy System Integrating Pre-Interventional Magnetic Resonance Imaging and Live Ultrasound Fusion. Journal of Urology [Internet]. 2011 Dec 1 [cited 2025 Dec 8];186(6):2214–20. Available from: https://doi.org/10.1016/j.juro.2011.07.102